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Protein Folding : Examining the Challenges From Synthesis to Folded Form

By: Alka Dwevedi. Series: SpringerBriefs in Biochemistry and Molecular Biology. Cham [Switzerland] : Springer. 2015. eBook., Database: eBook Index

The book will discuss classes of proteins and their folding, as well as the involvement of bioinformatics in solving the protein folding problem. In vivo and in vitro folding mechanisms are exami...


Protein NMR : Modern Techniques and Biomedical Applications

By: Lawrence Berliner. Series: Biological Magnetic Resonance, volume 32. New York : Springer. 2015. eBook., Database: eBook Index

This book covers new techniques in protein NMR, from basic principles to state-of-the-art research. It covers a spectrum of topics ranging from a “toolbox” for how sequence-specific resonance ass...


Protein-Protein Interactions : Principles and Techniques: Volume I

By: Krishna Mohan Poluri; Khushboo Gulati; Sharanya Sarkar. Edition: 1st ed. 2021. Singapore : Springer. 2021. eBook., Database: eBook Index

This book provides a comprehensive overview of the fundamental aspects of protein-protein interactions (PPI), including a detailed account of the energetics and thermodynamics involved in these i...


Protein Engineering Techniques : Gateways to Synthetic Protein Universe

By: Krishna Mohan Poluri; Khushboo Gulati. Series: SpringerBriefs in Applied Sciences and Technology, Forensic and Medical Bioinformatics, Forensic and medical bioinformatics. Singapore : Springer. 2017. eBook., Database: eBook Index

This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods. It also presents various computational programs with applications...


Lipids in Protein Misfolding

By: Olga Gursky. Series: Advances in Experimental Medicine and Biology, volume 855. Cham : Springer. 2015. eBook., Database: eBook Index

​Protein conversion from a water-soluble native conformation to the insoluble aggregates and fibrils, which can deposit in amyloid plaques, underlies more than 20 human diseases, representing a m...


Practical Protein Bioinformatics

By: Florencio Pazos; Mónica Chagoyen. Cham [Switzerland] : Springer. 2015. eBook., Database: eBook Index

This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results...


SARS-CoV-2 Spike Protein Convergent Evolution : Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines

By: Daniele Focosi. Series: SpringerBriefs in Microbiology. Cham : Springer. 2021. eBook., Database: eBook Index

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike...


Food Protein Induced Enterocolitis (FPIES) : Diagnosis and Management

By: Terri Faye Brown-Whitehorn; Antonella Cianferoni. Edition: 1st ed. 2019. Cham : Springer. 2019. eBook., Database: eBook Index

This unique book is a first-of-its-kind resource, comprehensively guiding readers through the epidemiology, pathophysiology, recent diagnostic criteria, and management options for patients with F...


The Unfolded Protein Response in Cancer

By: Robert Clarke. Series: Cancer Drug Discovery and Development. Edition: 1st ed. 2019. Cham : Humana. 2019. eBook., Database: eBook Index

This volume presents state-of-the-art information on each of the arms of the unfolded protein response (UPR), how their activation/repression are regulated, integrated, and coordinated, how UPR c...


Scalable Big Data Analytics for Protein Bioinformatics : Efficient Computational Solutions for Protein Structures

By: Dariusz Mrozek. Series: Computational Biology, volume 28. Cham : Springer. 2018. eBook., Database: eBook Index

This book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels an...


A Metaheuristic Approach to Protein Structure Prediction : Algorithms and Insights From Fitness Landscape Analysis

By: Nanda Dulal Jana; Swagatam Das; Jaya Sil. Series: Emergence, Complexity and Computation, Vol. 31. Cham : Springer. 2018. eBook., Database: eBook Index

This book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm ...


Data Analytics for Protein Crystallization

By: Marc L. Pusey; Ramazan Savaş Aygün. Series: Computational Biology, vol. 25. Cham : Springer. 2017. eBook., Database: eBook Index

This unique text/reference presents an overview of the computational aspects of protein crystallization, describing how to build robotic high-throughput and crystallization analysis systems. The ...


From Protein Structure to Function with Bioinformatics

By: Daniel J. Rigden. Edition: Second edition. The Netherlands : Springer. 2017. eBook., Database: eBook Index

This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function ba...


Total Synthesis of Thielocin B1 As a Protein-Protein Interaction Inhibitor of PAC3 Homodimer

By: Kosuke Ohsawa. Series: Springer Theses. Tokyo : Springer. 2015. eBook., Database: eBook Index

This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein–protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechani...


Fundamentals of Neurodegeneration and Protein Misfolding Disorders

By: Martin Beckerman. Series: Biological and Medical Physics, Biomedical Engineering. Edition: 1st ed. 2015. Cham : Springer. 2015. eBook., Database: eBook Index

This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few y...


High-Resolution Profiling of Protein-RNA Interactions

By: Mathias Munschauer. Series: Springer Theses. Cham : Springer. 2015. eBook., Database: eBook Index

The work reported in this book represents an excellent example of how creative experimentation and technology development, complemented by computational data analysis, can yield important insight...


Protein Ligation and Total Synthesis I

By: Lei Liu. Series: Topics in Current Chemistry, Vol. 362. Edition: 2015. Cham : Springer. 2015. eBook., Database: eBook Index

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years ar...


Protein Homology Detection Through Alignment of Markov Random Fields : Using MRFalign

By: Jinbo Xu; Sheng Wang; Jianzhu Ma. Series: SpringerBriefs in Computer Science. Cham : Springer. 2015. eBook., Database: eBook Index

This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular ho...


Heat Shock Protein-Based Therapies

By: Alexzander A.A. Asea; Naif N. Almasoud; Sunil Krishnan; Punit Kaur. Series: Heat Shock Proteins, Vol. 9. Cham : Springer. 2015. eBook., Database: eBook Index

The book Heat Shock Protein-Based Therapies provides the most up-to-date review on new heat shock protein-based mechanisms used in the therapy and treatment of various human disorders and disease...


Protein Modifications in Pathogenic Dysregulation of Signaling

By: Jun-ichiro Inoue; Mutsuhiro Takekawa. Tokyo : Springer. 2015. eBook., Database: eBook Index

This book is devoted to recent advances in analysis of the molecular basis and dynamics of post-translational modifications (PTMs) of proteins for a comprehensive understanding of their key roles...


Fundamentals of Protein Structure and Function

By: Engelbert Buxbaum. Edition: 2nd ed. 2015. Cham : Springer. 2015. eBook., Database: eBook Index

This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is expla...


Protein Kinase CK2 Cellular Function in Normal and Disease States

By: Khalil Ahmed; Olaf-Georg Issinger; Ryszard Szyszka. Series: Advances in Biochemistry in Health and Disease. Cham : Springer. 2015. eBook., Database: eBook Index

Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer. Mor...


Protein Ligation and Total Synthesis II

By: Lei Liu. Series: Topics in Current Chemistry, Vol. 363. Edition: 2015. Cham : Springer. 2015. eBook., Database: eBook Index

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years ar...


Protein Secondary Structure Graphs as Predictors for Protein Function

By: Frosina Stojanovska; Nevena Ackovska. In: ICT Innovations 2019. Big Data Processing and Mining : 11th International Conference, ICT Innovations 2019, Ohrid, North Macedonia, October 17–19, 2019, Proceedings. :187-201; Cham : Springer International Publishing, 2019. Language: English, Database: Springer Nature eBooks

Predicting the functions of the proteins from their structure is an active area of interest. The current trends of the secondary structure representation use direct letter representation of the s...


OntoPPI: Towards Data Formalization on the Prediction of Protein Interactions

By: Yasmmin Cortes Martins; Maria Cláudia Cavalcanti; Luis Willian Pacheco Arge; Artur Ziviani; Ana Tereza Ribeiro de Vasconcelos. In: Metadata and Semantic Research : 13th International Conference, MTSR 2019, Rome, Italy, October 28–31, 2019, Revised Selected Papers. :260-271; Cham : Springer International Publishing, 2019. Language: English, Database: Springer Nature eBooks

The Linking Open Data (LOD) cloud is a global data space for publishing and linking structured data on the Web. The idea is to facilitate the integration, exchange, and processing of data. The LO...